2024

^ Alzheimer’s Society: TIMP-3 Proteinopathy: A Novel Mechanism in Age-Associated Neurodegenerative Diseases – fellowship to Dr Jennifer Dewing. £218,099.86

2023

^ Fondation Leducq: A Translational Approach Towards Understanding Brain Waste Clearance in Cerebral Amyloid Angiopathy. 8 million USD. Southampton component: 984,889 USD

^ Romania’s National Recovery and Resilience Plan. Intramural cells as biomarkers and therapeutic targets for Alzheimer’s disease. EUR1.4million

^ Foundry Engineering, USA. HERV-K in neurological diseases £93,000

^ PhD Studentship Hashemite University, Jordan. Connections between the brain and the nose £100,000

2022

^ NIH” Perlecan Domain V as a therapeutic VCID strategy for the clearance of amyloid beta from the brain in cerebral amyloid angiopathy”, £ 76,645 (Co-PI)

2021

^ Codiak funded project “Exosomes in neurological diseases” £373,727

^ Alzheimer’s Research UK – Co-PI “Targeting perivascular innervation and vascular tone for improved clearance of ß-amyloid from the brain“. £88,440

^ VAXXINITY, “Effects of anti-tau immunization” £185,000

^ ALCYONE, “Patterns of distribution of AAV9” £142,335

^ PCE Romania- Clusterin as a therapeutic agent in Alzheimer’s disease 249,635 EUR

2020

^ Bright Focus (USA- award with Michigan State University) Noradrenergic regulation of amyloid clearance in AD. Total $285,000 . Southampton award: £109,647

^ Alzheimer’s Association (USA): Targeting cerebral smooth muscle cell mitochondria in Alzheimer’s disease $44,583

^ Japan Society of Science fellowship to Dr Satoshi Saito –  “Clusterin is a key molecule that improves intramural periarterial drainage“. £140,000

^Horizon 2020 TUBE-LC-MG-2018 – “Transport derived ultrafines and their brain effects“. £239,039     More info

^ Royal Society – “Lysyl oxidase (LOX) as a facilitator of intramural periarterial drainage of the brain“. £24,000

^ United Neuroscience project grant – “New immunisation strategies for Alzheimer’s disease“.£250,000

^ Medical Research Council UK & United Neurosciences  “Investigating immunisation strategies for the treatment of alpha synucleinopathies“.  £70,000

^ Medical Research Council UK & United Neurosciences  “Immunisation in alpha synucleinopathies“.  £70,000

^ Stroke Association Priority Programme Award (vascular dementia) – “Failure of drainage of fluid from the brain along the walls of blood vessels in vascular dementia“. £245,198.00

^ National Institute of Health, award to Binghamton, Cornell and Southampton Universities – “Interdisciplinary assessment of intramural periarterial drainage“. £51,700 (Southampton component)

^ Rosetrees Trust Project grant – “The effect of maternal high fat on the clearance of interstitial fluid from the brain“. £25,000

^ British Neuropathological Society – “Aquaporin in white matter abnormalities“. £15,000

^ BBSRC CASE PhD Studentship with Kirkstall Ltd – “Development of an in vitro perivascular clearance system“. £95,042

^ Alzheimer’s Research UK – Co-PI – “Targeting perivascular innervation and vascular tone for improved clearance of ß-amyloid from the brain“. £88,440

^ Biogen Ltd Project grant – “Determining the pattern of distribution of small molecules in the CSF“.  £60,000

^ Alzheimer’s Research UK Equipment Grant – co-applicant- Nano-Zoomer XR. £100,000

^ Biogen Ltd PhD studentship – “The connections between CSF and ISF compartments of the brain“. £75,000

^ Alzheimer’s Research UK Equipment Grant – Leica Confocal SP8. £100,000

^ Protea Biosciences – “Biomolecular imaging in offspring of maternal high fat“. £10,000

^ Invicro Ltd – “Age-related proteomic changes in the basement membranes of human brains“. £66,000

^ Invicro Ltd – “Study of the pattern of intracerebral distribution of small molecules“. £66,870

^ BBSRC Project grant – “Lymphatic drainage of ageing brains“. £600,000

^ RoseTrees Trust project grant – “Changes in the perivascular pathways for the elimination of amyloid from the ageing brains. Implications for new therapeutic strategies in Alzheimer’s Disease“. £24,000

^ Alzheimer’s Research UK, Network Cooperation Grant – “Age-related proteomic changes in the basement membranes of human brains“. £66,000

^ kirby Laing Foundation – “Epigenetic changes in offspring of maternal high fat“. £30,000

^ ARUK Cooperation Grant – Universities of Southampton (Carare R.O), Newcastle (Kalaria R, Attems J) and Kings College London (Ward M): “Age-related changes in the basement membranes of cerebral blood vessels: implications for Alzheimer’s disease“. £99,980

^ University of Southampton – Research Management Committee of the School of Medicine for the project entitled “Impeding the elimination of extracellular fluid and solutes from the brain: An experimental model to study the pathophysiology of Alzheimer’s disease“. £20,000

^ ART Fellowship Grant – “Drainage failure of fluid and solutes from the brain in Cerebral Amyloid Angiopathy: A prelude to Alzheimer’s disease“. £137,188